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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea25a9dab003beeac0761b28dc5d324fc11a58ffe31fc22a2312c16759b95cb8' 
  AND token = 'Vv0CPb1tO+3sISwhwMj3Qm6d37Z7E8S+DmG9t/SLQ8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}