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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6046b42caaaf9b597410cf7c4b91b3244b5a4bbbe3ca8bea79cab7067c6e59cc' 
  AND token = 'qAwI5v+9WxIA4z0oSDJS8ODLABvcVFWqcztJ3h5NoxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}