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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d505ef3a0d8cd8e9f7e076abb2373dac83b9f94b02f8d0912d5b6691aa2c441' 
  AND token = 'TjrLplz+/lhBMHoEQ5946k9TTqLuXXeUM3D2nc+X5Vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}