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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25eb5ee37bdc141194f3c928a3ead74b927f1cdd0f349d190f074b3fff6e10fa' 
  AND token = 'Ho20k+bT5zD2tMFR/HztMAlzytrZLj66W2gJFFMD5Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}