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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9829588213a5fcd15c1cca6f18fe27a5034778a0567b309bb02be5e661abf340' 
  AND token = 'GkVZti2O/ooSEEECB3VRRiPTWWC1QV8RYUR55o+NGIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}