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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b5dc49c217e25d558df5f87ba3d23f7c7896825bf4bfd46ae1a2f1483c1222' 
  AND token = 'PuAWO7Iy+bLw562tC7fWKYrvGpsL9hDE44mgq2ssDS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}