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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c4009ca3ab8d6ad18cbb1384f27053197901cced0e9fad1f1b5f428a9da946a' 
  AND token = 'cf9lLQ94U6Lr1Z7mrG9c+r9zZmoe1Sea+IG5YCr79uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}