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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e61f905107e09817376c980446844eda286a36db32b2d34279e26f46600c2d49' 
  AND token = 'IHAaCpt/tvwYtTz2zL0qDsC7tVQCoTza7sDqfjMwbyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}