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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33466e2a8e971d30231cb711b1d611323d22a5357b5fa3a8d7f9353179db580d' 
  AND token = 'XrGIeTVcKo8i5npOgrS5ygsoM26xH5+3NfkuVdiLzRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}