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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '584449464423c76745090a277e5cd0722bdfd70a6e4841a091a3a1abfb598f7a' 
  AND token = '39yujntCamLa/h4+4sw9cG2VXHduuxcC91COvMEKoG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}