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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f5d50d7dae4453e6b6f1b514186ea5ed5140600c12ed5909c462678961631f' 
  AND token = 'EUw3y3n+434yFf+nz3qHJDhCOnLXvfjhRC7HegV0Vyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}