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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fb49396843132949cb2e35f5f1d59a1c365d615f020e48b37cff6392b0d58dd' 
  AND token = 'o//0paUlmw9lqKNsxpYFm0zAUX166ZA23nhygD8pyYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}