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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ca125a1873a76a7f1b04c6497634a20af7340f55182219ea882788d1afb9bd' 
  AND token = 'EYv377WgTiltZsryIfwB6b5DFH/3y2lLvKczX0BHoEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}