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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5050adf2e26fa20d1344530f0cc55f1bd3647f754dd0d0c4c65b70da72535326' 
  AND token = '9EQ+Zd1xzDFYG13Y2qNGCTWW9jn9FzYBTNI0jD+lv9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}