SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3df4780343aec86adc9f40bad9ad46cbd78835ed303aff527e12628f1a5cfe4d' 
  AND token = '4X7LSi0croKDAsYIIoohCZqbfqfUIKrMHRi7l/qyDgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}