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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e61ed9926cca26e1c0df0a4200a4e6f7ea2ff80c03335a6e95f7d27871e6aef' 
  AND token = 'WeWQXw1tHWt78Qa+oVY+JJIXPRZ9lfZA36XoPquNCHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}