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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6217c0158f9ed18a8189550d1f921c0a2e36f7c79f557a61b495bfd000ef880' 
  AND token = '241uBi77NTNT585O3fgXKTWWBF4CthGBC/ARBlvCPzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}