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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d37edc48ac8eebf1d00ff7344ee1fa12a9931e0383bb8f52e56fde95d6ccc3f' 
  AND token = 'KdCrg+Db97R0SlIQd74YkFANcPcBxa27/WxTk+5cfOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}