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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a49186fd9b3377864fec4aac824b0bc11ef8ac605e6a2a5a2ee235a9d1eab2d' 
  AND token = 'd4xvo7yQoAEF4z6XWOiuY+MN6JBXRO0HR+/tsm87KQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}