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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1216e8ba472239c981b6b0d570996a7810595da9e20414c5e973283635211fc8' 
  AND token = '/x5ZqbI9aUmzQxEUJKh9xgRQnxZx8IfVqxEKJDpeZ/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}