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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8d8374a8c9a9285ef83fd51385420c369e6649e3de1af8c6bb8275e78256517' 
  AND token = '786HYjFtn2Bt/GQzGotjEqgmNT8nA3wMk4sgwjWv794=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}