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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fe2449e638d66e7a02ecd59b996e6d2a46e5a65376f5fd0925a1db4184eb91f' 
  AND token = '1kjTyd3adWReqPWXYxuVMOz+eWS4l2yxjK9malQ/k2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}