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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12281bc016d8ca248132436adba9791cf880892d95762fac7c1bfc5793f690c' 
  AND token = 'cSM7t37TJDlgzc0lUo7vASSXrjGF1zh7T/d7KrA0Acs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}