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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e21c1c5f06f5e23a66c3c906954462d47d69c3516ca47b753760d9c5c53a734' 
  AND token = '49z8ZwW8c12Cf1aZckjHIWSaee0cly3cH4P+BHGMQAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}