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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b1060e22f21c3c44f38b44a34b06a2b872c1830fa72877f78368f1a0d4c6465' 
  AND token = 'zsDvQWsa6n4+azOxaCmkIXfhZQQbL3WYuEBrQvKIe9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}