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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb00052e8d689219f916c7ed0f22a710c26b33adfb29e01019f2ce67e25875a0' 
  AND token = 'I5EnRNCp8n2EwusXL5hfn5VHtwgY40BlMAztG/oDglU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}