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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485b1d70f2c0668cd88e35f95e9d52570b306be4e3a43720e7393d52661e55c8' 
  AND token = 'zDKwxcepMpvGqzbMB+fv5ckKCCWU1XIQdpdgMtm2jr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}