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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af8dd61fcb72c9170bde8227263f7ca050a997b45e71f8228b1946e01b8b4d33' 
  AND token = 'E3s4GHCGIEUMNMw8tbmRTsttwo3eosGgDFr4cf+gz1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}