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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed521c9f69409ccee45468e39e09801281b8f08f1b90dae28ec2af69855c32b3' 
  AND token = 'VWmIWwgkZiuxMp2E+5s259r32N1p6OS+3KA8jxKlU5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}