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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4659cbbb65f3fe8aabcb13f6a4089e724c3ab8cd2f3f1d4545489da6b35938cc' 
  AND token = 't8rIxoNDYydQ+04xcdbruv/yM32TIcKNYbN2Bxpbzhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}