SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee9a0fafc53fb756ab738969930b5594bb81a7a0a184ec1b3d263160533bc600' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}