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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4218debe1d86d96257f35f4ba8c510c3a81004d2cf25a653e3b7b68fd74b1847' 
  AND token = 'NH8tyMwIIQogmbWl20C/nheQfbVksR8wCRiK44J/UAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}