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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f337dbb6b38dab001ad0786426f2007d533f0fc96e70e8170f5d0cf66ceedd13' 
  AND token = '49+KeY9zjLIl/t2+A7kSJMtMS5PuESQR2IWxkd/RibY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}