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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a41ac8df3ec7c42429318fd79efa6408f3d421f502f6c20bab6d0c305cf940' 
  AND token = 'KLFh3LCXyfZ/oOpZ0q905Yuf/1jP1tzfwvTjpOoj4Ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}