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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a9426ab94a41aa68617412c49876f99a30bf302a18ef71c048808bbc96bb79' 
  AND token = '3TUI+iFDXPUEFE+DRTEKmfIpJXSpZNsXjDfaPF+69Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}