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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '541a1c8b99ee9da88991447998b6a70e1e50e6135ad36f1cfcb12dd95d9e8dd1' 
  AND token = 'Six5QjQFwNGnDE389nl+q4y0ogOYpDy/ASiiW1cyoBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}