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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66b52c2cb4461a67b77073c52ae57040309cd5bed2b04c1689f8daca90c2f375' 
  AND token = 'rk2tfvTSs6rvp1mCcXwN8DhP4jU68+VXaEXFDpUTLoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}