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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af500052e938d222101d3e47fa0994fbfeacd9cfe3db0c18b4e1d69bc7cc3e5f' 
  AND token = 'pF18y/XKRFUU96GgFhzSBEMhGEnOz9GQ3DtKNw9Dv6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}