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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4841fa53763cc00ea9c0c9245eb12755c90f65773eb819194f296d65a6e8c2b' 
  AND token = 'E9zxIP9mhVk0oa3COkQtPnGAo5qHfH+DtMrDXLgM5Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}