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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448576bc3d917d9bc4454554b2b7dfdb53a5529429f4decbc457b5e33107a3ed' 
  AND token = 'GWc9zEt0o8nkjeWKig5u9IpYe5bcfMFSeqlQ4nOdwcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}