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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e189100ad9f0eebd8ab36ac26fd7b06b3ba7aa8655b29a6c033074c7c4edf8' 
  AND token = 'vRbmFMwBXvr1ruP4LQXB+eqtOMYvaXpdlkrF8R1Q/RI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}