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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b5a4c9e7f2989839bae48eb2727da07e60b7f105bbaa31f87651c242b16453' 
  AND token = 'Fq0AzFefabTM9AWgZf1+0wbub9cyehfs0ASj/XWuyjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}