SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52d1dbfdc58dde6aaa0e890ee6a388b12f87acb0292fc456b8b722fa2964136f' 
  AND token = 'quVESPzBaXYt8xBIqomEaqXf+q/Xy9xjfLR3tc4fosA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}