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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f52eccb75e56c9a50834368fb75eb166cf88c6b2e0b5b9ede139b65248cb4e2' 
  AND token = 'E66hJDOxbW2j6R++WADLJHpO3sui4mlHtMrMHY6GHSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}