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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c27b858ddf585ce09f350d74ca022bad87afef4488b2381c0b01e4e4cd3ddf20' 
  AND token = 'ermxC7/A/p38s3Jqx1c2hC8XZOonUzGH5MFVjiIWTkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}