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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5a43b72a2c13fbd80a8092450cea0e4109f762c5b412e7ef288340a030a8b64' 
  AND token = 'lak5CQbeZaNJgeFOK4SsdI7wv5vclg83+US/19aHSbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}