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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '047c66bdf3bc2d6fbdf54df8a3c22d7a66d50bc0b14100327774bd1e3afe901f' 
  AND token = '/E8SkDZeXpkRCtkM/D8/YYkTlk8I4NRTuEwlApALb2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}