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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0678dcdef6cf78e9aaf60726034939ca00cc034f83d1df0f24594f147cb22c3' 
  AND token = 'RekWzfsF9/VC4q6OqJvGOYVNbxbmJpfyLd/hmzWUxGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}