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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5832613a49d6b8c6229af35de5340746367db6509bcdc06b48b5f33956b02a3' 
  AND token = 'rrxGe9FCIyQcvgzrxH/2MOe87mq/ZKZpvDNLzQuaKd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}