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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c40c21ec5c2724bcfc3a0bd6588792075bf2ac9c813232322154d992fcea595' 
  AND token = 'nag5T5K1A95u031RhG3pa+saZNN780G/+mnoIgxMghM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}